Description
Regenerating islet-derived protein 4 (REG4) is also known as Gastrointestinal secretory protein (GISP), REG-like protein (RELP).
REG4 contains one C-type lectin domain.
REG4 has calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment.
REG4 may be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium